Available for Android and iOS devices. (9) (10) (11), Contrave is a tablet weight loss medication, whereas Saxenda is an injectable drug. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. This could increase the amount of beta-blocker in your body, which may raise your risk of side effects from the beta-blocker. Cannabidiol is not physically addictive in the same way opiates, cocaine, alcohol, and other drugs can be. However, you should limit your alcohol intake due to the risk of lactic acidosis with metformin. Education The most common side effects include diarrhea, vomiting, nausea, constipation, headache, or dry mouth. Related complications could include high blood pressure, high cholesterol, or type 2 diabetes. Find answers to some frequently asked questions about Contrave and possible interactions. How Do Gastric Sleeve and Gastric Bypass Surgeries Compare? If you become pregnant while taking Contrave, tell your doctor right away. Does my health history affect whether I should take Contrave? Comment * document.getElementById("comment").setAttribute( "id", "a3cde379f03b9d12046b7b320f701247" );document.getElementById("fdaf3f488c").setAttribute( "id", "comment" ); Your email address will not be published. Aspirin taken along with Depakote can cause negative interactions. 5 Things To Know Before Starting Weight Loss Medication, bupropion/naltrexone (Rx) https://reference.medscape.com/drug/contrave-bupropion-naltrexone-999933, Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Required fields are marked *. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Metformin has very few drug interactions but shouldnt be taken with iodinated contrast media, which is the most common interaction. Metformin is safe to take with most types of over-the-counter medication, but the patient should always consult with their health care provider for guidance and further medical advice if they have questions. But this doesnt mean that interactions with herbs wont be recognized in the future. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient. This drug is can treat malaria. There are currently no reports of Contrave interacting with vitamins. This is because Contrave may cause seizures as the dose increases. How it works: This company claims their supplement works on areas of the brain that process rewards and hunger to help you feel full appropriately. A glaucoma attack may cause sudden blurry vision and eye pain. In some cases, Contrave can cause suicidal ideation. series of articles on weight loss options, in-depth comparison of Contrave vs phentermine. Metformin dosages range from 500 milligrams to a maximum of 2,550 milligrams per day. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. Closed-angle glaucoma. Taking Contrave exactly as prescribed can also help prevent interactions. Other drugs that have the same active ingredients (e.g. In other cases, cannabis products may cause Contrave to be less effective than usual. Patients with a BMI <30 were required to have at least one of the following: dyslipidaemia, hypertension or drugnaive/metformintreated type 2 diabetes. However, it will put you at risk for accidental overdose. Health conditions or other factors that might interact with Contrave include: High blood pressure. Drug interactions are reported among people who take Contrave and Oxycodone together. They may give you a different type of test that isnt affected by bupropion. As part of a series of articles on weight loss options, will look in more detail at the ingredients, safety, and success rates of Contrave to help you decide if this medication might be right for you. But it can be taken with long-acting insulin. Everything You've Ever Wanted to Know About Bariatric Surgery, Average Age for Knee Replacement Surgery Is Dropping Due to Obesity, Study Highlights Need for Tailored Weight Loss Plans to Treat Obesity, can increase the risk of side effects from Contrave, can increase the risk of side effects from MAOIs, can raise the risk of side effects from SSRIs, can increase the risk of side effects from beta-blockers, can raise the risk of side effects from antiarrhythmics, can increase the risk of side effects from antipsychotics, can raise the risk of side effects from Contrave, can increase the risk of side effects from Contrave and levodopa, can increase the risk of side effects from Contrave and amantadine, can make tamoxifen less effective than usual, bupropion (Aplenzin, Forfivo XL, Wellbutrin SR, Wellbutrin XL). For questions regarding your prescription medication, we recommend consulting with your doctor or pharmacist. Certain health conditions or other factors could raise your risk of harm if you take Contrave. Contrave works on the food centers of the brain to reduce hunger, whereas Saxenda stimulates insulin production to suppress the appetite. So, taking it with alcohol produces a moderate to high drug . Taking these medications together could increase your risk of side effects from Contrave. Terms and Conditions and Privacy Policy. - Weight loss. One of the benefits of metformin is that it doesnt cause low blood sugar. (5), Contrave has been investigated in long-term clinical trials. By clicking subscribe, I agree to Bensnaturalhealth Usually avoid combinations; use it only under special circumstances. Its used alongside exercise and a balanced diet to help certain adults lose weight. (13). This article explains the factors that affect how long, Starting a weight loss journey alone can be difficult. No warnings were found for your selected drugs. Kidney or liver damage. Sharing this information with them may help prevent possible interactions. Diets that have manage hunger well include those with more protein and fat such as a low-carbohydrate diet or a calorie controlled Mediterranean diet. 2011; 19 (1): 110-120.7. There is also an extended-release version of metformin that is designed to be taken once daily. Patients in the study may take other drugs besides Contrave and Metformin. To view an interaction report containing 4 (or more) medications, please sign in or create an account. Learn about the most popular weight loss medications. Headaches and dizziness are some of the most common issues Ive observed. There are some concerns around seizure risks with drinking alcohol while on Contrave, but this risk appears to only be the case if you were a heavy drinker beforehand, then suddenly stopped drinking while on Contrave, since sudden alcohol withdrawal is well known to increase seizure risks. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Nutrition plays a big role in both physical and mental health, and I find joy in helping people reach their goals and notice a positive difference in how they feel. Highly clinically significant. Certain eating disorders. Excess insulin is a common trait among PCOS sufferers, which can lead to excess testosterone and disruption of ovulation. Thanks for your comment. Examples of these medications include barbiturates, benzodiazepines, and seizure drugs. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Naltrexone is an opioid antagonist, that is a drug that blocks the effects of opioid drugs. That means that you can safely take metformin with other types of medication for diabetes, including insulin and sulfonylureas. Costs: $99 - $115 (plus $45 doctor consultation fee) Active ingredients: bupropion and naltrexone. Applies to: Contrave (bupropion / naltrexone). How does Ozempic work? This article is for general informational purposes only. Contrave is one of the few weight loss pills approved by the FDA and available in Canada specifically for treating obesity. These medications are not usually taken together. Hydroxyzine interactions with alcohol is considered a food-drug interaction. This is because Contrave may cause seizures as the dose increases. (6). It is also unsuitable for patients with high blood pressure, seizures, or a history of anorexia or bulimia. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. However, the safety of Contrave in combination with other medications has not been established and so care must be taken if you take other drugs, including herbal remedies. Does Contrave interact with other medications? A false-positive means the test shows a positive result for a drug that is not actually present. You may also want to check out the online communities at Bezzy. It is important to tell your doctor about all other medications you use, including vitamins and herbs. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Email this report to a friend, doctor, or patient. 336 significant drug interactions. Interactions can also occur if you have certain health conditions. (1). Phen: yes, Met: no: Phentermine is a weight loss med that has been proven to be effective when combined with a reduction in caloric intake for 35 years or more, its safe,. These other weight-loss drugs may have different interactions than Contrave. Taking Aleve (naproxen) with metformin may increase the risk of lactic acidosis due to a potential decrease in kidney function. Notify me via e-mail if anyone answers my comment. Patients selfadministered three capsules containing either 2.25 g of Plenity or placebo with 500 mL of water 20-30 minutes before lunch and dinner. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. 7 Facts from our Contrave Review. If you have had an allergic reaction to Contrave or any of its ingredients, your doctor likely wont prescribe Contrave. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. If youve had an allergic reaction. Obesity (Silver Spring). Be sure to tell them if you have these side effects while taking the drugs together. MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge drinking or frequent consumption) should be avoided during treatment. Contrave is an anorexiant drug that is used to decrease the weight of the body by decreasing the appetite of a person. (12), If you dont want to take Contrave any longer, you can simply stop the pills. Before you start taking Contrave, talk with your doctor and pharmacist about any supplements, herbs, and vitamins you take. 11420039) is registered in UK, manufactures in the US and distributes globally. In July of Last year I was put on birth control pills to help with my diagnoses of PCOS. (8). Comparison of combined bupropion and naltrexone therapy for obesity with monotherapy and placebo. Amantadine is used to treat symptoms of Parkinsons disease. ", "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", Agitation (state of anxiety or nervous excitement), Dulcolax and Metoprolol Tartrate drug interaction, Glucagon and Systemic Inflammatory Response Syndrome. Here are 15 common weight loss mistakes to avoid. NSAIDs, like Aleve, can decrease kidney function and increase blood pressure. Side effects are more prevalent among patients struggling with a heart condition. I mean, Thats how the popular hair loss drug minoxidil, also known as Rogaine, was discovered. Bupropion may also make your body more sensitive to the effects of alcohol. These medications may cause some risk when taken together. When used alone, naltrexone is used to treat addiction, whereas bupropion is an antidepressant. Or they may prescribe a drug other than Contrave for you. Lactic acidosis is a serious condition where your body creates more lactic acid than your body can clear. After combining the two, they came up with Contrave, and after studies showed that both worked synergistically to help with weight loss, the FDA finally approved its use in 2014. Contrave (naltrexone/bupropion) is a prescription drug. I'm about to pick up my first prescription of Contrave. This combination is thought to reduce feelings of hunger and control cravings, supporting you to lose weight and keep it off. Consult with your primary care physician before combining any medications. Greenway FL, Dunayevich E, Tollefson G, et al. Contrave.com (How Contrave Works).4. Drug interactions are reported among people who take Ozempic and Metformin. Find out about possible interactions with alcohol, other drugs, supplements, foods, and more. If you take them together or do not wait 2 weeks, you may have confusion, agitation, restlessness, stomach or bowel symptoms, a sudden high body temperature, an extremely high blood pressure, or severe seizures. And Contrave can cause serious side effects, such as . If you need help understanding this information, your doctor or pharmacist can help. Sign in to your account to save this drug interaction list. It can cause both high and low blood sugar and isnt recommended for people with diabetes. Earlier this year, Consumer Reports took aim at Contrave, too: "Nearly 1 in 4 people in the clinical trials stopped taking the prescription weight loss pill because they couldn't tolerate the common side effects, including nausea, headache, and vomiting." They can tell you whether Contrave may affect the beta-blocker. These factors include if you take another drug that increases your risk of seizures or if you have a seizure disorder or a condition that may cause seizures. Topamax is an oral brand-name drug most often used as an anticonvulsant to treat epilepsy, but it is sometimes prescribed to reduce obesity. Metformin helps improve insulin sensitivity which helps lower blood sugar levels. Pregnant and breastfeeding women should not take Contrave. (If you did not get paperwork with Contrave, ask your pharmacist to print a copy for you.) Its important to note that you should avoid taking Contrave with high fat foods. Do not take any other medicines while you are taking CONTRAVE unless your healthcare provider has said it is okay to take them. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Contravehcp.com (Contrave FAQs).6. 2010; 376 (9741): 595-605.5. There arent any known significant metformin drug interactions for over-the-counter medications. Some reports may have incomplete information. Your doctor likely wont prescribe Contrave for you if youve recently been drinking alcohol excessively or youve suddenly stopped excessive drinking. Long story short, I developed a Massive Pulmonary Embolism in my lungs due to the contraceptives. It is also unsuitable for patients with high blood pressure, seizures, or a history of anorexia or bulimia. People tend to make many mistakes when they try to lose weight. its used by itself often to help recovering opioid addicts or alcoholics, to reduce their addiction to those substances. Although there is no specific diet you need to follow with Contrave, you will still need to have an effective weight loss diet you are already following, or plan to follow. (An active ingredient is what makes a drug work.) ALL RIGHTS RESERVED. Contrave.com (Contrave).2. Your doctor can recommend what to do if this happens. Get the best fitness, food, and weight loss tips to succeed on your journey! Like other drugs, Contrave may have interactions. Have you used Contrave for weight loss, and do you have experiences to share? Diana has worked as a dietitian in an inpatient hospital setting, where she assessed patients nutritional needs, recommended nutrition support, and offered nutrition education. - Reduced diabetes risk. One of the benefits of metformin is that it doesn't cause low blood sugar. There are currently no reports of Contrave interacting with herbs. Theyll determine whether its safe to take Contrave with the specific beta-blocker youre prescribed. Before taking Contrave, tell your doctor about any SSRIs you take. They may adjust your diabetes treatment plan. Its kind of a different type of appetite suppressant, in that, it seems to be more effective at suppressing cravings, rather than hunger. Questions you may want to ask your doctor include: To learn more about Contrave, see these articles: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. The study uses data from the FDA. Your doctor is not likely to prescribe Contrave while youre pregnant. So, you could decide on the best diet pill to help you lose weight. However, some people who do drink alcohol while on Contrave, report that it makes them feel sick, or that the alcohol doesnt seem to have the same effect. Learn more about certain drug interactions that can occur with Contrave. Typically it consists of bupropion and naltrexone, both of these are drugs of different classes. Contrave may also be useful for diets that involve some form of intuitive eating, such as listening closely to your bodys hunger signals before eating, as it can help to curb impulsive snacking and eating. It is often used in diabetes. 1. If you have certain eating disorders. If you have questions about taking Contrave with ibuprofen, talk with your doctor or pharmacist. 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